“Using SIFT-MS analysis, sub-part-per-billion detection limits for nitrosamines are achievable within seconds”


Vaughan Langford Syft Technologies Director - Applications & Marketing

Dr. Vaughan Langford

BSc(Hons), PhD


Principal Scientist / Consultant

Nitrosamines are often highly carcinogenic and yet they are surprisingly common. They are formed as by-products in a variety of industrial processes and carbon capture technologies. They are also found in tobacco (even before it is smoked!), cosmetics, and are formed when certain foods are cooked – most notably barbecued meats.

A couple of years ago, we published a paper in the International Journal of Mass Spectrometry that demonstrated rapid, high-sensitivity analysis of eight nitrosamines using Selected Ion Flow Tube Mass Spectrometry (SIFT-MS). The table eight summarize these nitrosamines and provides an overview of their occurrence in several, diverse applications.

The table summarize these nitrosamines and provides an overview of their occurrence in several, diverse applications.

The figure below shows the SIFT-MS full-scan mass spectrum of N-nitrosodimethylamine (NDMA), with product ions at 75 for H3O+ and 74 for NO+ and O2+. Sub-part-per-billion (by volume) detection limits are readily achievable for all of these nitrosamines within a matter of seconds.

Nitrosamines Analysis NDMA Scan with SIFT-MS

You can obtain a copy of the paper from the publisher, Elsevier.

If you would like more information on detection of nitrosamines using the revolutionary SIFT-MS technology contact us.

 Contact Us