SIFT-MS is an absolutely unique mass spectrometric technique, because ion energies are precisely controlled to provide reproducible, real-time quantitative analysis.
Rate coefficients for the reaction of the SIFT-MS reagent ions (H3O+, NO+, O2+, O–, O2–, OH–, NO2–, and NO3–) with target compounds allow quantitative analysis on all Syft instruments. Coupled with the measured count rate of reagent and product ions at the detector and the flow rate of the sample into the instrument, absolute concentrations are calculated in real time by the instrument software.
We’ve captured and utilized this fundamental advantage of SIFT-MS in our LabSyft software package. Rate coefficients and product branching information are all stored in our in-built library. The library information is utilized in several ways via the:
- Compound Library module, where kinetic data can be searched, viewed, entered, and edited.
- Method Editor module, which greatly simplifies method development and markedly reduces the preparation time prior to sample analysis.
- Upcoming Compound Identification module, for identification and quantification of compounds in full mass scan analyses.