High-throughput Volatile Compound Analysis for the Lab: Automated SIFT-MS

Vaughan Langford Syft Technologies Director - Applications & Marketing

Dr. Vaughan Langford

BSc(Hons), PhD

Principal Scientist / Consultant

Conventional laboratory volatile compound analysis typically utilizes chromatography-based techniques, which are slow and frequently require extensive sample preparation. By utilizing soft chemical ionization, Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) provides direct, rapid sample analysis with no or minimal sample prep required. When coupled with autosampler technology,  SIFT-MS yields very high sample throughputs (in excess of 100 samples per hour), including for challenging compounds like ammonia, formaldehyde, and hydrogen sulfide.

Very high-throughput headspace and gas analysis provides new opportunities for both contract and R&D laboratories serving a range of industries, from environmental analysis to food testing to pharma. Applications include:


  • Simple, automated aldehyde analysis in air and headspace
  • Residual solvent analysis in packaging and pharmaceuticals
  • Residual monomer

Participants Will Learn:

  • The fundamentals of the selected ion flow tube mass spectrometry (SIFT-MS) technique, including its ability to selectively and comprehensively analyze samples in one, simple procedure.
  • How automating SIFT-MS analysis can revolutionize analysis of organic and inorganic volatiles, delivering competitive advantage through time and cost savings.
  • How automated SIFT-MS turns headspace techniques that are cumbersome with chromatography (e.g., multiple headspace extraction) into practical, economical methodologies.

For more information on how SIFT-MS can help your business

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