Sample throughput is often a critical bottleneck for analysis of volatiles in contract testing or research laboratories. In particular, many volatiles—such as those with low polarity or low molecular weight—fall into an awkward gap between conventional gas and liquid chromatographic techniques (GC and LC).

Selected ion flow tube mass spectrometry (SIFT-MS) is an excellent solution to this problem and is an easy-to-adopt complement to GC and LC techniques. SIFT-MS is a form of direct mass spectrometry that provides real-time detection of volatile organic compounds and many inorganic gases to sub-part-per-billion concentrations (by volume; ppbV) without preconcentration, derivatization, or drying. Automation of SIFT-MS creates a high-throughput analytical tool that addresses these throughput challenges.

Join us for this webcast (the first of a four-part series), where we demonstrate the advantages of applying automated SIFT-MS to volatiles analysis in diverse matrices, from air to the headspace of polymers, soil, and water. SIFT-MS is not simply advantageous for throughput reasons; it can also support faster method optimization for conventional methods (such as headspace equilibration times). SIFT-MS is easy to adopt, easy to automate, and can be utilized in a manner analogous to traditional chromatographic methods.

Subsequent webcasts in this series build on these basic advantages of SIFT-MS, showing practical, proven strategies for adopting automated SIFT-MS in your routine analysis workflow. We will also include example data and case studies from a range of application areas from pharmaceutical to environmental analysis.

Key Learning Objectives:

  • The analytical challenges for volatiles analysis faced by laboratories that are using only chromatographic methods
  • How the challenges of volatiles analysis can be addressed using direct MS, which provides higher sample throughputs, faster method development and validation, and improved analysis of challenging volatiles such as formaldehyde and hydrogen sulfide
  • How the specific direct MS technique called SIFT-MS works
  • How SIFT-MS analysis can be automated across a wide range of lab applications, such as headspace analysis, sample bags, and thermal desorption tubes

Who Should Attend:

  • Laboratory managers and analysts in routine industrial and contract testing and research laboratories, particularly those working with the analysis of volatiles
  • Laboratory managers and analysts in pharmaceutical, biomedical, industrial, consumer product, and environmental laboratories