Conventional chromatographic methods for analysis of volatile organic compounds (VOCs) and inorganic gases are being challenged by faster and more direct analytical techniques. Selected ion flow tube mass spectrometry (SIFT-MS) is the leading contender among the real-time analysis techniques, because of its high selectivity and broad-spectrum analysis. When coupled with automated sampling systems, SIFT-MS provides significant throughput increases for both testing laboratories and quality assurance/quality control (QA/QC) in a process environment. In this paper, these benefits are illustrated for residual monomer analysis, using formaldehyde emissions from polyoxymethylene (POM) polymer to illustrate.